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13. Skin Repair Accelerators Used for Hair Transplantation (Graftcyte, Folligen) :: Posted Thursday, May 24, 2001 by admin ::
A new product, GraftCyte, sold by ProCyte Corporation, when used in the post-operative regimen has resulted in faster healing of transplants and earlier regrowth of the hair shafts. GraftCyte is a copper peptide based on the Iamin tissue regenerative concept. (For details, see Copper Peptide Regeneration.) The GraftCyte dressing provides enhanced healing of the transplanted follicle. It results in less post-operative shedding along with a more immediate hair growth. Patients often see new hair growth in 6 weeks versus the normal 10 to 14 weeks. The normal skin crusting after transplantation has been reduced from 10 to 14 days to 5 days in most cases. GraftCyte costs about $275 per procedure and can be obtained from www.procyte.com/.
In a study of Graftcyte by Perez-Meza et al, (International Journal of Cosmetic Surgery (Vol. 6, 1998, pp 80-84), it was found that men and women receiving transplants and using GraftCyte for post-operative treatment achieved better results and a quicker healing time in comparison the conventional saline gauze dressing used after surgery. In a placebo-controlled, double blinded study of twelve patients were studied over a 13 week period, each patient received 16 treatments during 4 days post-surgery. On each patient, one side of the head was treated with conventional and the other with Graftcyte. Each patient received a conventional saline gauze dressing on one side of the head and GraftCyte on the other in a pre-assigned random scheme. Weekly results were documented by photographs and video microscopic scans. The study measured edema (excess fluid buildup and crusting), effluvium (shedding of transplanted hair), erythema (redness of the skin), the growth of transplanted hair that did not shed, and the regrowth of transplanted hair that returned after shedding plus overall cosmetic results.
In the Graftcyte treated areas, 42% of patients were found to exhibit less redness and crusting than on the placebo side vs 17% who were better with the saline; on the placebo side. Redness and crusting were slightly milder in the Graftcyte treated group (75% none to mild for GraftCyte and 58% for placebo). The GraftCyte treated side showed better hair regrowth at 4, 8, and 12 weeks compared to the placebo side. The patients felt that the GraftCyte treated hairs had greater body, shine, and texture than the placebo-treated side.
Other more advanced copper-peptide skin and hair growth accelerators are also available from such as Protect & Restore and Folligen which some physicians used after transplant. These accelerators have been proven effective in skin repair studies, and stimulate hair growth in mouse models, but as yet have not undergone controlled studies on hair transplantation.
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